MA32025: Medical statistics
[Page last updated: 22 May 2025]
| Academic Year: | 2025/26 |
| Owning Department/School: | Department of Mathematical Sciences |
| Credits: | 5 [equivalent to 10 CATS credits] |
| Notional Study Hours: | 100 |
| Level: | Honours (FHEQ level 6) |
| Period: |
- Semester 1
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| Assessment Summary: | EXCB 100% |
| Assessment Detail: |
- Closed-book written examination (EXCB 100%)
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| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
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| Requisites: |
Before taking this module you must ( take MA22014 AND take MA22015 ) OR take MA20227 OR take MA20302
In taking this module you cannot take MA30086
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| Learning Outcomes: |
By the end of the module you will be able to:
- understand the ethical considerations and governance problems related to medical studies.
- design a clinical trial to compare a new treatment against a control, that meets a stated power requirement and protects against possible sources of bias
- analyse survival data subject to right censoring
- interpret statistical analyses presented in a medical journal article
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| Synopsis: | You will study the principles of randomisation and experimental design in the context of medical studies. You will learn how to analyse survival data subject to censoring, a common form of response variable in clinical trials.
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| Content: | Revision of statistical tests set in a medical context and introduction of non-parametric tests.
Design of medical studies and ethical considerations.
Clinical trials: phases I to IV of drug development.
Sample size calculation
Parallel arm, cross-over, case-control and cohort designs
Protecting against bias: randomization, blinding, "intention to treat" analysis.
Missing data, estimands
Relative risks and odds ratios, Mantel-Haenszel test
Survival analysis: censoring, the hazard function, Kaplan-Meier estimator, log-rank test, Cox's proportional hazards model.
Presentation of results.
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| Course availability: |
MA32025 is Compulsory on the following courses:
Department of Mathematical Sciences
- USMA-AFB32 : BSc(Hons) Mathematics and Statistics (Year 3)
- USMA-AAB02 : BSc(Hons) Mathematics and Statistics with Study year abroad (Year 4)
- USMA-AKB02 : BSc(Hons) Mathematics and Statistics with Year long work placement (Year 4)
MA32025 is Optional on the following courses:
Department of Computer Science
- USCM-AFB32 : BSc(Hons) Computer Science and Mathematics (Year 3)
- USCM-AAB20 : BSc(Hons) Computer Science and Mathematics with Study year abroad (Year 4)
- USCM-AKB20 : BSc(Hons) Computer Science and Mathematics with Year long work placement (Year 4)
- USCM-AFM32 : MComp(Hons) Computer Science and Mathematics (Year 3)
- USCM-AKM32 : MComp(Hons) Computer Science and Mathematics with professional placement (Year 3)
- USCM-AKM32 : MComp(Hons) Computer Science and Mathematics with study abroad (Year 3)
Department of Economics
- UHES-AFB12 : BSc(Hons) Economics and Mathematics (Year 3)
- UHES-AAB04 : BSc(Hons) Economics and Mathematics with Study year abroad (Year 4)
- UHES-AKB04 : BSc(Hons) Economics and Mathematics with Year long work placement (Year 4)
- UHES-ACB04 : BSc(Hons) Economics and Mathematics with Combined Placement and Study Abroad (Year 4)
Department of Mathematical Sciences
- USMA-AAB16 : BSc(Hons) Mathematical Sciences with Study year abroad (Year 4)
- USMA-AKB16 : BSc(Hons) Mathematical Sciences with Year long work placement (Year 4)
- USMA-AFB30 : BSc(Hons) Mathematics (Year 3)
- USMA-AAB14 : BSc(Hons) Mathematics with Study year abroad (Year 4)
- USMA-AKB14 : BSc(Hons) Mathematics with Year long work placement (Year 4)
- USMA-AFB33 : BSc(Hons) Mathematics, Statistics and Data Science (Year 3)
- USMA-AAB20 : BSc(Hons) Mathematics, Statistics, and Data Science with Study year abroad (Year 4)
- USMA-AKB20 : BSc(Hons) Mathematics, Statistics, and Data Science with Industrial Placement (Year 4)
- USMA-AFM30 : MMath(Hons) Mathematics (Year 3)
- USMA-AKM15 : MMath(Hons) Mathematics with Year long work placement (Year 4)
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Notes: - This unit catalogue is applicable for the 2025/26 academic year only. Students continuing their studies into 2026/27 and beyond should not assume that this unit will be available in future years in the format displayed here for 2025/26.
- 好色tv and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
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