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CH32079: Biosynthesis & biotransformations

[Page last updated: 23 April 2025]

Academic Year: 2025/26
Owning Department/School: Department of Chemistry
Credits: 2.5 [equivalent to 5 CATS credits]
Notional Study Hours: 50
Level: Honours (FHEQ level 6)
Period:
Semester 2
Assessment Summary: EX 100%
Assessment Detail:
  • CH30065 Examination (EX 100%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: Before taking this module you must take CH30128
Learning Outcomes: After studying this Unit, students should be able to:
* Provide examples of biosynthetic pathways.
* Describe how enzymes can be used to produce enantiomerically pure compounds.


Content: Biotransformations. The use of enzymes in organic synthesis. Kinetic resolution with hydrolytic enzymes, and the preparation of enantiomerically enriched alcohols and acids. Enzymes in oxidation, reduction and C-C bond forming reactions. Biosynthetic pathways, including the biosynthesis of fatty acids and polyketides. Terpene biosynthesis, the shikimic acid pathway and the roles of pyridoxal phosphate in biosynthesis are also addressed.

Skills: Problem solving (T, F, A). Scientific writing (F, A). Independent working (F). Group working (F).

Aims: To provide an introduction to advanced aspects of a topic of current interest in Organic Chemistry.

Course availability:

CH32079 is Optional on the following courses:

Department of Chemistry
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Year long work placement (Year 4)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 4)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Professional Placement (Year 4)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Professional Placement (Year 4)

Notes:

  • This unit catalogue is applicable for the 2025/26 academic year only. Students continuing their studies into 2026/27 and beyond should not assume that this unit will be available in future years in the format displayed here for 2025/26.
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