好色tv

- Academic Registry


CH32018: Synthesis, development and design of pharmaceuticals

[Page last updated: 23 April 2025]

Academic Year: 2025/26
Owning Department/School: Department of Chemistry
Credits: 15 [equivalent to 30 CATS credits]
Notional Study Hours: 300
Level: Honours (FHEQ level 6)
Period:
Academic Year
Assessment Summary: CWES 17%, CWPG 17%, CWRI 33%, EXCB 33%
Assessment Detail:
  • Hit to lead report (CWRI 33%)
  • Essay (CWES 17%)
  • Group synthesis (CWPG 17%)
  • Closed-book written examination (EXCB 33%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: Before taking this module you must take CH22011
Learning Outcomes: Outline the reagents, conditions and reaction mechanisms of relevant transformations for the synthesis and functionalisation of heterocyclic compounds; Analyse and solve problems relating to the multi-step synthesis of small organic molecules; Evaluate and propose synthetic routes to small-molecule drug targets; Evaluate and propose strategies used for the development of major blockbuster drugs and discuss the factors that contribute to their success in the market; Plan and propose a hit-to-lead drug development strategy based upon analysis and evaluation of biological data.


Synopsis: This unit will cover key reactions and approaches towards the synthesis and functionalisation of core motifs within small molecular drugs. Case studies on the discovery and development of major blockbuster drugs will be discussed. You will also participate in a hit-to-lead drug design exercise using your knowledge of different areas of the drug discovery process.

Content: This unit will include the following topics: Reactions for the synthesis of heterocycles; Reactions for the functionalisation of heterocycles Multicomponent reactions; Development of blockbuster drugs (case studies); Virtual drug-design exercise.

Course availability:

CH32018 is Compulsory on the following courses:

Department of Chemistry
  • USCH-AFB21 : BSc(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AFM21 : MChem(Hons) Chemistry for Drug Discovery (Year 3)

Notes:

  • This unit catalogue is applicable for the 2025/26 academic year only. Students continuing their studies into 2026/27 and beyond should not assume that this unit will be available in future years in the format displayed here for 2025/26.
  • 好色tv and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.